
Suicide is preventable and never inevitable. Regardless of this, greater than 720,000 individuals die by suicide yearly, and there are a lot of extra individuals who will make a suicide try of their lifetime (World Well being Organisation, 2024). It’s nicely established that suicide entails a posh and dynamic interplay of organic, psychological, environmental, and socio-cultural elements (O’Connor, 2011). Nonetheless, a wealth of proof has demonstrated the sturdy affiliation between psychiatric issues, together with main depressive dysfunction, character issues and psychotic issues, and elevated threat of suicide amongst completely different populations (Baldessarini & Tondo, 2020; Bradvik, 2018).
Notably, mainstream suicidology, psychiatric and medical disciplines have usually theorised dying by suicide to be the tip results of psychiatric issues, or psychological diseases (Hjelmeland & Jaworski, 2019; White, 2017). Nonetheless, as Marsh (2016) asserts, these claims have typically been framed as ‘unassailable truths’ which have dominated views on suicide, and subsequently additionally suicide prevention efforts. Critically although, it has been argued that the complexity and socio-cultural formation of suicidality can’t be understood, or responded to, inside this attitude (White, 2017). As such, you will need to emphasise that a person who has skilled suicidal misery, or survived a suicide try, might not have additionally skilled psychiatric issues or psychological sickness. This truth reminds us that discourses of threat, moderately than an individual’s particular person lived experiences or wants, have typically framed our understanding of suicidal misery, thus limiting our responses to suicide prevention.
Within the present examine, Oquendo and colleagues (2024) aimed to deal with the shortage of obtainable proof on lifetime suicide makes an attempt amongst in any other case wholesome people, who had not met the factors for any psychiatric issues previous to their first try.

Is suicide merely the ‘finish consequence’ of psychological sickness or can it happen exterior of psychological sickness?
Strategies
The researchers carried out secondary evaluation of present cross-sectional information utilizing the US Nationwide Epidemiological Research of Addictions and Associated Situations III (NESARC-III), a nationally consultant population-based survey from 2012-2013. The general pattern was comprised of 36,309 members who had been aged between 20 and 65 years previous. Amongst those that had skilled a lifetime suicide try, the intention was to estimate the share of individuals whose first suicide try occurred earlier than the onset of any psychiatric dysfunction. Knowledge evaluation was carried out utilizing SAS, and the primary outcomes and measures had been:
- Demographics together with age group, intercourse, race and ethnicity
- Lifetime suicide try frequencies amongst total pattern (n=36,309)
- Among the many sub-sample (n=1948), who had been people who had skilled a lifetime suicide try, the self-reported presence or absence of a psychiatric dysfunction earlier than the primary lifetime suicide try
- Amongst sub-sample, separate analyses for intercourse variations (male/feminine), and age variations had been additionally carried out (20-34, 35-49, and 50-65 years)
Outcomes
From the general pattern of 36,309 members, 1948 people had skilled a number of suicide makes an attempt of their lifetime (5.2%; 95% CI, 4.8% to five.6%). From this sub-sample, 66.8% (95% CI, 64.1% to 69.4%) had been feminine, and 33.3% (95% CI, 30.6% to 35.9%) had been male. The overwhelming majority of those members had been White (70.9%), and the others had been Hispanic (14%), Black (9.8%), American Indian or Alaska Native (3.5%), and Asian, Native Hawaiian or Different Pacific Islander (1.8%).
Contributors with none psychiatric prognosis
The examine reported that 6.2% (95% CI, 4.9% to 7.4%) of members who had made a suicide try of their lifetime didn’t meet the factors for a lifetime psychiatric dysfunction on the time of the survey administration. Moreover, an estimated 13.4% (95% CI, 11.6% to fifteen.2%) of people had reported that their first suicide try occurred earlier than any psychiatric dysfunction onset. Due to this fact, an estimated complete of 19.6% respondents within the sub-sample had skilled a suicide try of their lifetime with out an antecedent psychiatric dysfunction.
Intercourse variations
Notably, there have been no vital intercourse variations within the share of people with lifetime suicide makes an attempt who didn’t have a psychiatric dysfunction, nor in these reporting a lifetime suicide try earlier than the onset of any psychiatric dysfunction. Nonetheless, females (n=195) had been extra more likely to have made a suicide try throughout the identical yr because the onset of their first psychiatric dysfunction (14.9%; 95% CI, 12.5% to 17.3%) than males. Furthermore, males (n=410) had been extra more likely to have made a suicide try after the onset of a psychiatric dysfunction (70%; 95% CI, 65.2% to 74.9%) in comparison with females (60.3%; 95% CI, 56.9% to 63.7%).
Age variations
There have been no vital variations throughout the three age teams in relation to the chance of reporting a lifetime suicide try and not using a psychiatric dysfunction, nor had been there any vital variations within the onset of suicide makes an attempt throughout the lifespan relative to the onset of psychiatric diagnoses between the three specified age teams.

This analysis means that not all individuals who have made a suicide try of their lifetime have skilled psychiatric issues, or psychological sickness.
Conclusions
The authors conclude that:
These information recommend that suicide risk-reduction methods attending solely to people with psychiatric issues, even when these methods had been to end in good detection and prevention, would miss about 20% of people that go on to try suicide.

Focussing suicide prevention efforts solely on those that have beforehand skilled a psychiatric dysfunction would miss round 20% of people that go on to try suicide.
Strengths and limitations
This cross-sectional examine supplies us with essential and novel findings which reveal that not all individuals who make a suicide try of their lifetime could have skilled psychiatric issues, or psychological sickness, previous to their suicide try (19.6%). Though the examine analysed information from a considerable total pattern of 36,309 people, the sub-sample of those that had made a suicide try of their lifetime (n=1948) was comparatively small for a cross-sectional examine of this nature. Moreover, cross-sectional research have inherent limitations in relation to establishing trigger and impact, susceptibility of bias, and self-reporting bias the place members might misreport data. Furthermore, because the writer acknowledges, the NESARC-III survey doesn’t embrace all diagnoses akin to autism spectrum, obsessive-compulsive, and intermittent explosive issues that are related to elevated chance of suicide makes an attempt throughout ones’ lifetime (Hirvikoski et al., 2019; Pellegrini et al., 2020).
Given their findings, the authors go a way in the direction of suggesting that suicidal behaviour might not essentially be pathological. Nonetheless, additionally they assert that suicide makes an attempt might “manifest like different psychiatric issues, which are sometimes comorbid with one another” (p.576). Moreover, they suggest that suicidal behaviour be recorded as a separate psychiatric dysfunction, which might result in a uniform definition and a diagnostic code which might be helpful for clinicians. Though this advice has optimistic implications for suicide threat screening, and thus suicide prevention, different students have challenged the notion that suicidal behaviour is inevitably pathological, and that it ought to be categorised as a psychiatric dysfunction (Hjelmeland & Jaworski, 2019; Marsh, 2016; White, 2017).

Whereas the massive total pattern measurement strengthens the findings, limitations embrace a small sub-sample of suicide attempters, self-reporting bias, and excluded diagnoses, elevating essential questions on how we outline and deal with suicidal conduct
Implications for apply
The findings of this cross-sectional examine have vital implications for medical apply, policymakers, future analysis, and suicide prevention insurance policies or methods. Oquendo and colleagues recommend {that a} historical past of suicidal behaviour or suicide makes an attempt ought to be recorded by clinicians, no matter whether or not a person has a psychiatric prognosis or not. That is significantly essential since a earlier historical past of suicidal behaviour has been proven to be related to an elevated chance of future makes an attempt, and dying by suicide. The authors additionally recommend that recording suicidal behaviour as a separate psychiatric dysfunction might result in a extra uniform definition and diagnostic code, which can show helpful for suicide prevention.
The present suicide threat discount methods are usually not detecting an estimated one-fifth of people who’ve skilled a suicide try of their lifetime. Consequently, suicide threat screening ought to be expanded past psychiatric populations and people who have a pre-existing psychological sickness prognosis. Clinicians and psychological well being professionals ought to be conscious that suicidal behaviour might manifest individually, or as comorbidities related to psychiatric issues or psychological sickness and will subsequently receive and document the historical past of a person’s experiences with suicidal behaviour, no matter whether or not the particular person has a pre-existing psychiatric dysfunction or not.
Well being and social care insurance policies ought to take into account implementing broader screening protocols for suicide threat amongst completely different populations. It could be helpful for screening to happen at hospitals, physician surgical procedures, behavioural well being organisations, and different healthcare settings. Well being and social care insurance policies ought to take into account implementing broader screening protocols for suicide threat amongst completely different populations. It could be helpful for screening to happen at hospitals, physician surgical procedures, behavioural well being organisations, and different healthcare settings.
There stays restricted analysis on suicide threat amongst populations that don’t have a pre-existing psychiatric dysfunction or psychological sickness. Future analysis may discover the complicated elements which can be related to elevated chance of suicide try amongst this inhabitants, utilizing nationwide healthcare information. Utilizing nationwide healthcare information might enhance affected person security, enhance care and subsequently cut back suicide threat.

This analysis means that it might be useful to display screen everybody for earlier experiences of suicide, not simply these with present psychiatric diagnoses.
Assertion of pursuits
The writer has no competing pursuits to declare.
Hyperlinks
Main paper
Oquendo MA, Wall M, Wang S, Olfson M, Blanco C. Lifetime Suicide Makes an attempt in In any other case Psychiatrically Wholesome People. JAMA Psychiatry. 2024;81(6):572–578. doi:10.1001/jamapsychiatry.2023.5672
Different references
Baldessarini, R. J., & Tondo, L. (2020). Suicidal dangers in 12 DSM-5 psychiatric issues. Journal of affective issues, 271, 66-73.
Brådvikm, L. (2018). Suicide threat and psychological issues. Worldwide journal of environmental analysis and public well being, 15(9), 2018.
Hirvikoski, T., Boman, M., Chen, Q., D’Onofrio, B. M., Mittendorfer-Rutz, E., Lichtenstein, P., … & Larsson, H. (2020). Particular person threat and familial legal responsibility for suicide try and suicide in autism: a population-based examine. Psychological medication, 50(9), 1463-1474.
Hjelmeland, H., Jaworski, Okay., Knizek, B., & Marsh, I. (2019). Problematic recommendation from suicide prevention specialists. Moral Human Psychology and Psychiatry, 20(2), 79-85.
Marsh, I. (2016). Critiquing Up to date Suicidology. In J. White, I. Marsh, M. Kral, & J. Morris (Eds.), Vital Suicidology—Reworking suicide analysis and prevention for the twenty first century (pp. 15–30). UBC Press.
Probert-Lindström, S., Bötschi, S., & Gysin-Maillart, A. (2024). The affect of therapy latency on suicide-specific therapy outcomes. Archives of suicide analysis, 28(3), 1009-1021.
Pellegrini, L., Maietti, E., Rucci, P., Casadei, G., Maina, G., Fineberg, N. A., & Albert, U. (2020). Suicide makes an attempt and suicidal ideation in sufferers with obsessive-compulsive dysfunction: A scientific evaluation and meta-analysis. Journal of affective issues, 276, 1001-1021.
White, J. (2017). What can essential suicidology do? Dying Research, 41(8), 472–480. https://doi.org/10.1080/07481187.2017.1332901.
World Well being Organisation. (2024). Suicide. https://www.who.int/news-room/fact-sheets/element/suicide.